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Prolia is a prescription medication used to treat osteoporosis in postmenopausal women and men at high risk for fracture. It works by inhibiting bone resorption and helping to maintain bone mass. Prolia comes in the form of injections administered by a healthcare provider about every 6 months. Here are some frequently asked questions about Prolia injections:
Prolia is approved by the FDA to treat osteoporosis in postmenopausal women who are at high risk for fracture as well as to increase bone mass in men with osteoporosis at high risk for fracture. It can also help treat bone loss caused by certain hormone therapies used to treat breast and prostate cancer.
Prolia works by inhibiting osteoclasts, which are the cells responsible for breaking down old bone. By reducing osteoclast activity, Prolia helps slow bone loss and maintain bone density and strength. This lowers the risk of fractures of the hip, spine and non-spine.
Prolia comes as a single-dose prefilled syringe or single-dose vial that requires preparation before injection. It is given as a subcutaneous injection, meaning it is injected under the skin, usually in the thigh, abdomen or upper arm. Injections are administered by a healthcare provider about every 6 months.
Common side effects of Prolia include back pain, pain in the arms or legs, high cholesterol, muscle pain, and bladder infection. Serious side effects are rare but can include osteonecrosis of the jaw and atypical fractures of the femur. As with all medications, patients should discuss any side effects or concerns with their doctor.
Many health insurance plans require prior authorization for Prolia to confirm medical necessity before approving coverage. Patients should contact their insurance provider to determine if a prior authorization is needed before receiving Prolia injections. The doctor's office may be able to assist with obtaining the necessary authorization.
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